The common definition of statistical significance as a P-value of 0.05 or less is incomplete. As this article explains, study power must also be considered. Statistical significance should be determined using positive predictive value, which accounts for P-value and power. With lower power, lower P-values are needed for significance.
Citation: Heston TF, King JM. Reevaluating statistical significance: the role of study power. World J Methodol. 2017 Dec 26;7(4):112-116. doi: 10.5662/wjm.v7.i4.112.